CRYO-EM RESOURCES

State-of-the-art Technology & Training

The Reichow Laboratory offers a world-class environment for structural biologists – with onsite access to multi-scale imaging facilities, the Pacific Northwest Center for Cryo-EM, and high-performance computing resources.

OHSU MULTISCALE MICROSCOPY CORE

The Reichow Lab provides truly exceptional opportunities for access and training with cutting-edge technologies in cryo-EM. A major research focus at OHSU involves the development and application of high-resolution imaging technologies directed toward the advancement of biomedical research. This focus is met with a world-class Multi-Scale Microscopy Core (MMC) that provides access, training and support to state-of-the-art electron microscopy imaging platforms. 

PACIFIC NORTHWEST CENTER FOR CRYO-EM

The RLSB is also the site of the NIH-sponsored Pacific Northwest Center for Cryo-EM (PNCC). The PNCC is one of the three national cryo-EM centers in the United States, which were developed to provide researchers access to the most advanced cryo-EM technologies in the world, and to provide user-training to enable the next generation of cryo-EM specialists to tackle the most challenging problems in biology and combat disease. Dr. Reichow is one of the Principal Investigators at the PNCC, and is involved in overseeing the management and strategic planning of center resources, and coordinating user out-reach, access and training activities.

HIGH-PERFORMANCE COMPUTING

Our laboratory has access to high-performance computing resources to support our cryo-EM image processing workflows and molecular dynamics simulation studies. The OHSU Advanced Computing Center (ACC) provides high-end CPU/GPU computing, research data storage servers and expert system administrators to help manage these resources and provide training to users. The Reichow Lab also houses several GPU-based computing nodes for in-house image processing and MD simulation work.