CRYO-EM RESOURCES

State-of-the-art Technology & Training

The Reichow Laboratory offers a world-class environment for structural biologists – with onsite access to multi-scale imaging facilities, the Pacific Northwest Center for Cryo-EM, and high-performance computing resources.

OHSU MULTISCALE MICROSCOPY CORE

The Reichow Lab provides truly exceptional opportunities for access and training with cutting-edge technologies in cryo-EM. A major research focus at OHSU involves the development and application of high-resolution imaging technologies directed toward the advancement of biomedical research. This focus is met with a world-class Multi-Scale Microscopy Core (MMC) that provides access, training and support to state-of-the-art electron microscopy imaging platforms. 

PACIFIC NORTHWEST CENTER FOR CRYO-EM

OHSU is also the site of the NIH-sponsored Pacific Northwest Center for Cryo-EM (PNCC). The PNCC is one of the three national cryo-EM centers in the United States, which were developed to provide researchers access to the most advanced cryo-EM technologies in the world, and to provide user-training to enable the next generation of cryo-EM specialists to tackle the most challenging problems in biology and combat disease. Dr. Reichow currently serves as a Principal Investigator at the PNCC, involved in overseeing the management and strategic planning of center resources, and coordinating user outreach, access and training activities.

HIGH-PERFORMANCE COMPUTING

Our laboratory has access to high-performance computing resources to support our cryo-EM image processing workflows and molecular dynamics simulation studies. The OHSU Advanced Computing Center (ACC) provides high-end CPU/GPU computing, research data storage servers and expert system administrators to help manage these resources and provide training to users. The Reichow Lab also houses several GPU-based computing nodes for in-house image processing and MD simulation work.